COMPARISON OF THE VASOACTIVITY OF AMIDE AND ESTER LOCAL ANAESTHETICS
نویسندگان
چکیده
منابع مشابه
Comparison of the vasoactivity of amide and ester local anaesthetics. An intradermal study.
The vascular effects and duration of action of two ester-linked local anaesthetics, procaine and amethocaine, and four amide-linked local anaesthetics, cinchocaine, lignocaine, mepivacaine and prilocaine, were investigated in 10 volunteers by intradermal injection using a double-blind technique. Procaine and amethocaine produced marked vasodilatation; weal formation was observed at 80% of the a...
متن کاملNeurotoxicity Comparison of Two Types of Local Anaesthetics: Amide-Bupivacaine versus Ester-Procaine
Local anaesthetics (LAs) may lead to neurological complications, but the underlying mechanism is still unclear. Many neurotoxicity research studies have examined different LAs, but none have comprehensively explored the distinct mechanisms of neurotoxicity caused by amide- (bupivacaine) and ester- (procaine) type LAs. Here, based on a CCK8 assay, LDH assay, Rhod-2-AM and JC-1 staining, 2',7'-di...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1985
ISSN: 0007-0912
DOI: 10.1093/bja/57.10.1006